Cellular Internalization and Cytotoxicity of Aptamers Selected from Lung Cancer Cell
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چکیده
منابع مشابه
Cellular Internalization and Cytotoxicity of Aptamers Selected from Lung Cancer Cell
In this work, single-stranded DNA (ssDNA) aptamers against EGFR-transfected A549 cells, one type of non-small cell lung cancer (NSCLC) cells, were selected by cell-SELEX (systematic evolution of ligands by exponential enrichment) and were evaluated. The selected aptamers had high affinity to the A549 cells with dissociation constants in the nanomolar rang. Moreover, the aptamers were able to in...
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ژورنال
عنوان ژورنال: American Journal of Biomedical Sciences
سال: 2013
ISSN: 1937-9080
DOI: 10.5099/aj130100047